Explore how mitochondria become sites of Aβ accumulation in Alzheimer's disease, driving free radical generation and oxidative damage in disease progression.
Explore how mitochondrial microRNAs (mitomiRs) act as critical communication links between cellular energy production and obesity-related metabolic dysfunction.
Discover how mercuric chloride disrupts mitochondrial transport in axons, causing neural traffic jams and energy crises in the nervous system.
Discover how alcohol triggers acute pancreatitis through mitochondrial dysfunction and endoplasmic reticulum stress, with scientific data and visualizations.
Discover how mitochondrial dysfunction in immune cells drives ulcerative colitis and the promising new precision therapies targeting cellular energy production.
Explore how mitochondrial function and protein kinase C play distinct roles in vascular calcification, a key process in artery hardening.
Discover how induced pluripotent stem cells from aged donors retain mitochondrial aging signatures, challenging our understanding of cellular reprogramming and rejuvenation.
Explore the fascinating role of PGC-1α as the master regulator of skeletal muscle metabolism, mitochondrial biogenesis, and its therapeutic potential for metabolic diseases.
Exploring how HIV and HCV co-infection causes severe mitochondrial dysfunction compared to HCV mono-infection, accelerating cellular aging and liver damage.
Discover how hydrogen sulfide (H₂S) acts as a master metabolic reprogrammer by directly rewiring mitochondria through Electron Transport Chain (ETC) plasticity.